Selective cross-linking of coinciding protein assemblies by in-gel cross-linking mass-spectrometry
Johannes F Hevler, Marie V Lukassen, Alfredo Cabrera-Orefice, Susanne Arnold, Matti F Pronker, Vojtech Franc, Albert J.R. Heck
This paper introduces IGX-MS, a cross-linking workflow combining blue native PAGE and in-gel cross-linking mass spectrometry, to analyze co-occurring protein complexes with reduced artificial over-length cross-links.
bioRxiv · Jul 10, 2020Biochemistry