Distinct distributions of myosin motor conformations during contraction of slow and fast skeletal muscle
Cameron Hill, Michaeljohn Kalakoutis, Alice Arcidiacono, Yanhong Wang, Emma Smith, Elisabetta Brunello, Luca Fusi, Malcolm Irving
The paper uses X-ray diffraction to show that fewer myosin motors are attached to actin in slow compared to fast skeletal muscle, revealing distinct structural and signaling mechanisms.
The Journal of Physiology · Apr 20, 2026Peer-reviewedBiophysics