AMPK promotes induction of a tumor suppressor FLCN through activation of TFEB independently of mTOR
Caterina Collodet, Marc Foretz, Mária Deák, Laurent Bultot, Sylviane Métairon, Benoı̂t Viollet, Gregory C. Lefebvre, Frédéric Raymond, Alice Parisi, Gabriele Civiletto, Philipp Gut, Patrick Descombes, Kei Sakamoto
The paper identifies the AMPK-TFEB-FLCN axis as a regulator of cellular and metabolic homeostasis through gene expression and functional studies in mice and zebrafish.
The FASEB Journal · Aug 12, 2019Peer-reviewedMolecular Biology