Author

Gabriele Civiletto

École PolytechniqueORCID 0000-0002-9818-9942Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:zebrafish· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Philipp GutiD· 3 shared Alice Parisi· 2 shared Giulia Lizzo· 2 shared Aline Charpagne· 1 shared Anselm A. ZdebikiD· 1 shared Benjamin Weger· 1 shared Benoı̂t ViolletiD· 1 shared Bruce Spiegelman· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersPharmacology & Toxicology

Philipp GutORCID

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3 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintAug 26, 2025

Whole-organism screening in a zebrafish model of CLN2 disease identifies pregnenolone as a modulator of lysosomal functions with anti-epileptic properties

Lisa Kiani, Gabriele Civiletto, Giulia Lizzo…·Claire Russell

This study identifies pregnenolone as a therapeutic candidate for CLN2 disease by suppressing seizures and normalizing lysosomal function in tpp1-/- zebrafish.

DOI 10.1101/2025.08.26.670480

zebrafishexperimental assay

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Molecular BiologyThe FASEB JournalPeer-reviewedAug 12, 2019

AMPK promotes induction of a tumor suppressor FLCN through activation of TFEB independently of mTOR

Caterina Collodet, Marc Foretz, Mária Deák…·Kei Sakamoto

The paper identifies the AMPK-TFEB-FLCN axis as a regulator of cellular and metabolic homeostasis through gene expression and functional studies in mice and zebrafish.

74 citations

mousezebrafish

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PhysiologybioRxivPreprintDec 7, 2018

PGC1a and Exercise Adaptations in Zebrafish

Alice Parisi, Peter Blattmann, Giulia Lizzo…·Philipp Gut

This study shows that PGC1a induces mitochondrial biogenesis and exercise-like adaptations in zebrafish, revealing conserved exercise responses and novel ETC organization.

DOI 10.1101/483784

zebrafishproteomics

𝕏 PostBluesky