Nuclear and cytoplasmic huntingtin inclusions exhibit distinct biochemical composition, interactome and ultrastructural properties
Nathan Riguet, Anne‐Laure Mahul‐Mellier, Niran Maharjan, Johannes Burtscher, Marie Croisier, Graham William Knott, Janna Hastings, Alice Patin, Veronika Reiterer, Hesso Farhan, Sergey Nasarov, Hilal Ahmed Lashuel
The paper examines the biochemical composition, interactome, and ultrastructural properties of nuclear and cytoplasmic Htt inclusions in mammalian cells and neurons.
Nature Communications · Nov 12, 2021Peer-reviewedNeuroscience