Author

Hesso Farhan

Innsbruck Medical UniversityORCID 0000-0002-0889-8463Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1 Molecular Biology· 1 Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Alvaro Köhn‐LuqueiD· 2 shared Johannes ZschockeiD· 2 shared Salim GhannoumiD· 2 shared Veronika ReitereriD· 2 shared Waldir Leoncio Netto· 2 shared Alice Patin· 1 shared Amirabbas Parizadeh· 1 shared Anders StåhlbergiD· 1 shared

Activity by Year

2021-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersSystems Biology

Alvaro Köhn‐LuqueORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

TXNIP mediates LAT1/SLC7A5 endocytosis to reduce amino acid uptake in cells entering quiescence

Jennifer Kahlhofer, Nikolas Marchet, Kristian Zubak, Brigitta Seifert, Madlen Hotze, Anna-Sophia Egger, Lucija Kucej, Claudia Manzl, Yannick Weyer, Sabine Weys, Martin Offterdinger, Sebastian Herzog, Veronika Reiterer, Chiara Volani, Marcel Kwiatkowski, , David Teis

The paper identifies TXNIP as a regulator of amino acid uptake during cellular quiescence by mediating endocytosis of the LAT1/SLC7A5 transporter.

The EMBO Journal · Oct 20, 2025Peer-reviewedCell Biology

Mitochondrial cardiolipin metabolism controlled by tafazzin enables ferroptosis

Yvonne Wohlfarter, Judith Hagenbuchner, Utku Horzum, Gregor Oemer, Andreas Winter, Markus Seifert, Julian Schwärzler, Janik Kokot, Pablo Hernansanz‐Agustín, Viktorija Jurić, Luiz Felipe Garcia Suoza, Heribert Talasz, José Antonio Enríquez Domínguez, Hesso Farhan, Timon E. Adolph, , Markus Andreas Keller

The paper shows that tafazzin deficiency in Barth Syndrome protects against ferroptosis by altering mitochondrial cardiolipin metabolism, affecting VDAC function and reducing ROS availability for ferroptosis.

bioRxiv · Oct 25, 2024 · PreprintMolecular Biology

Nuclear and cytoplasmic huntingtin inclusions exhibit distinct biochemical composition, interactome and ultrastructural properties

Nathan Riguet, Anne‐Laure Mahul‐Mellier, Niran Maharjan, Johannes Burtscher, Marie Croisier, Graham William Knott, Janna Hastings, Alice Patin, Veronika Reiterer, Hesso Farhan, Sergey Nasarov, Hilal Ahmed Lashuel

The paper examines the biochemical composition, interactome, and ultrastructural properties of nuclear and cytoplasmic Htt inclusions in mammalian cells and neurons.

Nature Communications · Nov 12, 2021Peer-reviewedNeuroscience

CellMAPtracer: A user-friendly tracking tool for long-term migratory and proliferating cells

Salim Ghannoum, Kamil Antos, Waldir Leoncio Netto, Cecil J. Gomes, Alvaro Köhn‐Luque, Hesso Farhan

CellMAPtracer tracks migratory and proliferating cells with a user-friendly interface, enabling accurate long-term analysis of cell division and migration patterns.

Cells · Feb 22, 2021Peer-reviewedSystems Biology

DIscBIO: a user-friendly pipeline for biomarker discovery in single-cell transcriptomics

Salim Ghannoum, Waldir Leoncio Netto, Damiano Fantini, Benjamin Ragan-Kelley, Amirabbas Parizadeh, Emma Jonasson, Anders Ståhlberg, Hesso Farhan, Alvaro Köhn‐Luque

DIscBIO is an open-source R pipeline that simplifies scRNA-seq analysis by integrating multiple tools for biomarker discovery and differential analysis.

International Journal of Molecular Sciences · Jan 30, 2021Peer-reviewedBioinformatics