ImmunologybioRxivPreprint
Balance of AKT isoforms in intestinal barrier function. Implications for IBD therapy.
Teresa García Prieto, Antonio Barbáchano, Natalia Cuesta…·Manuel Fresno
This study shows that balancing Akt1 and Akt2 isoforms regulates intestinal barrier function and inflammation, with Akt2 inhibition improving IBD symptoms in mice.
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