Intron retention as a novel source of cancer neoantigens
Alicia C. Smart, Claire A. Margolis, Harold Pimentel, Meng Xiao He, Diana Miao, Dennis Adeegbe, Tim Fugmann, Kwok-Kin Wong, Eliezer M. Van Allen
This paper identifies intron retention as a new source of cancer neoantigens and shows that retained intron neoantigen burden correlates with immune checkpoint blockade response.
bioRxiv · Apr 27, 2018 · PreprintCancer Biology