Author

Tim Fugmann

Max Delbrück CenterORCID 0000-0002-7447-7480Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alicia C. Smart· 1 shared Claire A. MargolisiD· 1 shared Dennis AdeegbeiD· 1 shared Diana MiaoiD· 1 shared Eduardo EyrasiD· 1 shared Eliezer M. Van AlleniD· 1 shared Ferrán SanziD· 1 shared Harold PimenteliD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Alicia C. Smart

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2 papers

Recent·Most cited

ISOTOPE: ISOform-guided prediction of epiTOPEs in cancer

Juan L. Trincado, Marina Reixachs‐Solé, Judith Pérez‐Granado, Tim Fugmann, Ferrán Sanz, Jun Yokota, Eduardo Eyras

ISOTOPE identifies tumor-specific splicing-derived epitopes using RNA sequencing and mass spectrometry, showing splicing neoepitopes have higher MHC-I binding affinity in immune responders.

PLoS Computational Biology · Sep 16, 2021Peer-reviewedBioinformatics

Intron retention as a novel source of cancer neoantigens

Alicia C. Smart, Claire A. Margolis, Harold Pimentel, Meng Xiao He, Diana Miao, Dennis Adeegbe, Tim Fugmann, Kwok-Kin Wong, Eliezer M. Van Allen

This paper identifies intron retention as a new source of cancer neoantigens and shows that retained intron neoantigen burden correlates with immune checkpoint blockade response.

bioRxiv · Apr 27, 2018 · PreprintCancer Biology