Author

Alisa Truong

Stanford University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Amy LiiD· 2 shared AradhanaiD· 2 shared Gaelen T. HessiD· 2 shared Josh TyckoiD· 2 shared Alexandro E. TrevinoiD· 1 shared Anshul Bharat KundajeiD· 1 shared Braeden K. EgoiD· 1 shared Carley I Schwartz· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersGenomics

Amy LiORCID

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2 papers

Recent·Most cited

Towards optimizing diversifying base editors for high-throughput studies of single-nucleotide variants

Carley I Schwartz, Nathan S. Abell, Amy Li, Aradhana, Josh Tycko, Alisa Truong, Stephen B. Montgomery, Gaelen T. Hess

The paper evaluates how base editor design features affect editing efficiency and mutation patterns in mammalian cells, identifying DivA-BE as the most effective variant.

bioRxiv · Nov 18, 2024 · PreprintGenomics

Identification and mitigation of pervasive off-target activity in CRISPR-Cas9 screens for essential non-coding elements

Josh Tycko, Michael Wainberg, Georgi K. Marinov, Oana Ursu, Gaelen T. Hess, Braeden K. Ego, Aradhana, Amy Li, Alisa Truong, Alexandro E. Trevino, Kaitlyn K. Spees, David Yao, Irene M. Kaplow, Peyton Greenside, David W. Morgens, , Michael Cory Bassik

The paper identifies off-target effects in CRISPR-Cas9 screens for non-coding elements and shows that strict filtering with specificity scores improves the identification of essential regulatory regions.

Nature Communications · Sep 6, 2019Peer-reviewedGenomics