An assessment of LRRK2 serine 935 phosphorylation in human peripheral blood mononuclear cells in idiopathic Parkinson’s disease and G2019S LRRK2 cohorts
Shalini Padmanabhan, Thomas A. Lanz, Donal N. Gorman, Michele Wolfe, Alison P. Joyce, Carlos Cabrera, Rosemary F. Lawrence-Henderson, Najah Levers, Neal Joshi, Thong Chi Ma, Christopher Liong, Sushma Narayan, Roy N. Alcalay, Samantha J. Hutten, Marco A. S. Baptista, Kalpana Merchant
The paper assesses pS935 LRRK2 levels in PBMCs of iPD and G2019S LRRK2 carriers, finding reduced levels in G2019S carriers with PD compared to those without PD or iPD.
Journal of Parkinson s Disease · Jan 28, 2020Peer-reviewedNeuroscience