Kalpana Merchant

This study shows that LRRK2 and GCase regulate BMP release via EVs, with mutant LRRK2 increasing EV-associated BMP and GCase modulating this effect.

This study investigates the role of SORL1 genetic variants in AD, RD, and PD across diverse populations, identifying variants associated with risk but no significant cumulative effect.

The paper uses proteomics and machine learning to identify potential biomarkers in cerebrospinal fluid for Parkinson's disease, showing altered protein levels and neuroinflammation signatures.

This study uses urinary proteomics and machine learning to identify biomarkers for stratifying Parkinson's disease patients and LRRK2 mutation carriers.

The paper assesses pS935 LRRK2 levels in PBMCs of iPD and G2019S LRRK2 carriers, finding reduced levels in G2019S carriers with PD compared to those without PD or iPD.