Author

Allan C. Powe

Vertex Pharmaceuticals (United Kingdom)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Georgia B. McGaugheyiD· 1 shared Jade ShiiD· 1 shared Thomas E. ClevelandiD· 1 shared Vijay S. PandeiD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMolecular Biology

Georgia B. McGaugheyORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

CFTR misfolds during native-centric simulations due to entropic penalties of native state formation

Jade Shi, Thomas E. Cleveland, Allan C. Powe, Georgia B. McGaughey, Vijay S. Pande

This study uses molecular dynamics simulations to show that CFTR misfolds due to entropic penalties, even in wild-type forms, and suggests this contributes to disease in mutants like F508del.

bioRxiv · Jun 28, 2018 · PreprintMolecular Biology