Short Tandem Repeat stutter model inferred from direct measurement of in vitro stutter noise
Ofir Raz, Tamir Biezuner, Adam Spiro, Shiran Amir, Lilach Milo, Alon Titelman, Amos Onn, Noa Chapal-Ilani, Liming Tao, Tzipy Marx, Uriel Feige, Ehud Y. Shapiro
The paper develops a Markov model to predict STR stutter noise from direct in vitro measurements, improving genotyping accuracy in single-cell and targeted-enrichment contexts.
Nucleic Acids Research · Jan 2, 2019Peer-reviewedBioinformatics