Targeting CDK12/CYCLIN K induces HIV gene activation and latency reversal which is mediated by P-TEFb
Praveenkumar Murugavelu, Heli Glebko, Jagrity Rani, Nili Tickotsky, Liron Levin, Alona Kuzmina, Ran Taube
This study shows that targeting CDK12/CYCLIN K induces HIV gene activation and latency reversal through P-TEFb-mediated mechanisms.
bioRxiv · Feb 13, 2026 · PreprintMicrobiology