Alpha Amatya

Simons Sleep Project (SSP): An open science resource for accelerating scalable digital health research in autism and other psychiatric conditions

The Simons Sleep Project provides a dataset of sleep and behavioral data from autistic adolescents and their siblings, showing that objective sleep measures like sleep onset latency differ between groups and correlate with behavioral severity.

Integrating de novo and inherited variants in over 42,607 autism cases identifies mutations in new moderate risk genes

The paper identifies 60 new moderate risk genes for autism by integrating de novo and inherited variants across 42,607 cases and 236,000 controls.

Exome sequencing of 457 autism families recruited online provides evidence for novel ASD genes

The paper reports exome sequencing of 457 ASD families, identifying 10.4% with known ASD genes and 3.4% with possibly associated variants, and provides statistical support for 34 ASD risk genes using the TADA framework.