Template strand deoxyuridine promoter recognition by a viral RNA polymerase
Alec Fraser, Maria L. Sokolova, Arina V. Drobysheva, Julia Gordeeva, Sergei I. Borukhov, Tatyana Artamonova, AlphaFold Team, Konstantin Severinov, P.G. Leiman
This study elucidates how the AR9 bacteriophage's non-virion RNA polymerase recognizes uracil-containing promoters in the template strand of dsDNA through a unique structural mechanism.
Nature Communications · Jun 20, 2022Peer-reviewedMolecular Biology