Author

Alvaro Martinez Guimera

Newcastle University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

D Shanley· 1 shared Daryl P. ShanleyiD· 1 shared Hannah O’KeefeiD· 1 shared James WordsworthiD· 1 shared L. Pease· 1 shared R-L. Scanlan· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 10 mutual co-author links

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1 shared paperSystems Biology

D Shanley

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2 papers

Recent·Most cited

Systems BiologybioRxivPreprintAug 16, 2022

Systematic transcriptomic analysis and temporal modelling of the senescent human fibroblast

R-L. Scanlan, L. Pease, Hannah O’Keefe…·James Wordsworth

The paper systematically analyzes transcriptomic data from human fibroblasts to identify gene expression patterns associated with different senescence types and models temporal protein changes.

1 citation

humanbulk RNA-seq

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Systems BiologybioRxivPreprintSep 4, 2019

Understanding biological ageing in terms of constitutive signals: Convergence to an average decrease in cellular sensitivity and information transmission

Alvaro Martinez Guimera, Daryl P. Shanley

The paper argues that biological ageing involves a decrease in cellular sensitivity and information transmission due to accumulated damage, leading to increased noise in biological networks.

1 citation

𝕏 PostBluesky