14-3-3s reduce propagation and toxicity of pathologic alpha-synuclein in the in vivo preformed fibril model
Rachel Underwood, Mary A. Gannon, Aneesh Pathak, Navya Kapa, Sidhanth Chandra, Alyssa Klop, Talene A. Yacoubian
This study shows that 14-3-3{theta} reduces alpha-synuclein toxicity and aggregation in an in vivo preformed fibril model, improving behavioral and neuronal outcomes.
bioRxiv · Nov 17, 2020 · PreprintNeuroscience