Cancer BiologyNature CommunicationsPeer-reviewed
SFPQ-TFE3 gene fusion reciprocally regulates mTORC1 activity and induces lineage plasticity in a novel mouse model of renal tumorigenesis
Kaushal V. Asrani, Adrianna Amaral de Aragao Mendes, Juhyung Woo…·Tamara Levin Lotan
This study creates a mouse model of SFPQ-TFE3-driven renal tumors and shows it induces lineage plasticity through mTORC1 activation.
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