Tamara Levin Lotan

The paper examines subclonal complete loss of CDKN1B in prostate cancer, finding higher prevalence in African American individuals and associations with worse outcomes.

This study identifies Src-mediated upregulation of EphA2 in PTEN-deficient cells and shows that combined AKT and Src inhibition synergistically suppresses tumor growth.

This study creates a mouse model of SFPQ-TFE3-driven renal tumors and shows it induces lineage plasticity through mTORC1 activation.

This paper evaluates B7-H3 expression across prostate cancer subtypes and identifies it as a stable target for ADC and ICI due to its low heterogeneity and negative regulation by androgen signaling.