Genetic analysis of praziquantel response in schistosome parasites implicates a Transient Receptor Potential channel
Winka Le Clecʼh, Frédéric D. Chevalier, Ana Carolina Alves de Mattos, Amanda Strickland, Robbie Diaz, Marina McDew‐White, Claudia M. Rohr, Safari Kinung’hi, Fiona Allan, Bonnie Lee Webster, Joanne P. Webster, Aidan Mark Emery, David Rollinson, Amadou Garba Djirmay, Khalid M. Al Mashikhi, , Timothy J. C. Anderson
The paper identifies a transient receptor potential channel (Sm.TRPMPZQ) as the genetic basis for variation in praziquantel response in Schistosoma mansoni.
Science Translational Medicine · Dec 22, 2021Peer-reviewedGenetics