NMDA receptor-dependent Hebbian plasticity refines hippocampal spatial representations during two-dimensional navigation learning
Ronen Reshef, Mina Shahi, Victoria Ho, Matthias Ollivier, Ahmet Arac, Ariel Cohen, David Yamin, Amanda Tran, Ruth Tjondropurnomo, Baljit S. Khakh, Daniel Aharoni, Thomas J. O’Dell, Peyman Golshani
This study shows that NMDA receptor-dependent synaptic plasticity is essential for refining hippocampal spatial representations during two-dimensional navigation learning.
bioRxiv · Jul 15, 2026 · PreprintNeuroscience