Baljit S. Khakh

The paper identifies aggrecan as an extracellular matrix protein that stabilizes fear memories by altering neuronal excitability in the hippocampal dentate gyrus.

This study shows that NMDA receptor-dependent synaptic plasticity is essential for refining hippocampal spatial representations during two-dimensional navigation learning.

This study identifies astrocyte-derived MFG-E8 as a key mediator of microglial synapse elimination in Alzheimer's disease mouse models, showing its role in synapse loss and potential as a therapeutic target.

This study shows that calcium signaling in oligodendrocytes is critical for shaping myelin sheath morphology during myelination in the developing mouse CNS.

The paper shows that astrocyte Ca2+ signaling amplifies sustained functional hyperemia in awake mice, but not brief responses, through distinct mechanisms.

This study shows that astrocyte leaflet structure, regulated by Ezrin, affects memory strength by controlling glutamate diffusion and synaptic function in the hippocampus.

This study examines how neuroinflammation affects astrocyte gene expression in the mouse medial prefrontal cortex and links these changes to anhedonia, finding shared pathways with human major depressive disorder and Alzheimer's disease.

iAChSnFR, a fluorescent indicator built from a bacterial periplasmic binding protein, reports acetylcholine with large, fast signals in mouse, fish, fly and worm preparations.

CaImAn, an open-source library, automates motion correction, source extraction, deconvolution and cross-session registration for calcium imaging, detecting neurons near human level (F1 0.75 batch, 0.76 online).

This study investigates spatial coding and neural synchronization in epilepsy using in vivo calcium imaging and network modeling, finding impaired spatial processing and desynchronized firing in epileptic mice.