P-glycoprotein exofection between fetal and maternal cells as a mechanism of intercellular material transfer at the feto maternal interface
Madhuri Tatiparthy, Amanda Wang, Vineeth Mahajan, Pilar Flores‐Espinosa, Emmanuel Amabebe, Tilu Jain Thomas, Xiao-ming Wang, Lauren S. Richardson, Ramkumar Menon, Ananth Kumar Kammala
The paper identifies exofection as a novel mechanism where fetal exosomes restore P-gp function in maternal cells, improving xenobiotic clearance and protecting the fetus.
bioRxiv · Jan 4, 2026 · PreprintDevelopmental Biology