Madhuri Tatiparthy

This paper demonstrates that trophoblast-derived extracellular vesicles can restore P-gp function in brain endothelial cells, enhancing Aβ clearance and reducing neuroinflammation in Alzheimer's disease models.

This study shows that prenatal exposure to bacterial extracellular vesicles (bEVs) enhances fetal gut immunity by promoting progenitor expansion and differentiation, with effects influenced by microbiota.

The paper identifies exofection as a novel mechanism where fetal exosomes restore P-gp function in maternal cells, improving xenobiotic clearance and protecting the fetus.