Coordination of membrane synthesis with cell growth: the Escherichia coli phospholipid synthesis enzyme PlsB responds to membrane abundance in a manner consistent with filamentation-mediated inhibition
Jaïrus Beije, Desi Fierlier, Margot Guurink, Amba Stapert, Adja Damba Zoumaro-Djayoon, Gregory Bokinsky
The paper shows that PlsB in E. coli forms inactive filaments in response to membrane abundance, coordinating phospholipid synthesis with cell growth.
bioRxiv · Nov 3, 2025 · PreprintMicrobiology