Iron Regulates CD4 T Cell Quiescence by Controlling TGF-β Production
Amber L. Siglin, Zelong Han, Afia Nkansah, Wanjun Chen, Cheong‐Hee Chang
This study shows TGF-β regulates CD4 T cell quiescence and iron homeostasis through TGFβR1 signaling, with iron overload enhancing TGF-β sensitivity and affecting regulatory T cell function.
bioRxiv · Jun 23, 2026 · PreprintImmunology