Cardiac microtubules mediate transverse (t)-tubule growth and homeostasis
Alice S. Whitley, George W. P. Madders, Amelia Livesey, Aaliya Ashik, Keita Uchida, Benjamin L. Prosser, Andrew W. Trafford, Katharine M. Dibb
This study shows that cardiac microtubules regulate t-tubule formation and maintenance through BIN1-CLIP-170 and dynein mechanisms, impacting Ca handling and contractile function.
bioRxiv · Aug 19, 2026 · PreprintPhysiology