Sex-specific effects of chronic unpredictable stress on mitochondrial function in the HPA axis in mice
Alexia M. Crockett, Noelle I. Frambes, Alaina Mullaly, Amelia M. Churillo, Rinaldo Rodrigues dos Passos, Cameron Folk, Lisa Freeburg, Eliana Cavalli, Josephine Gardiner, Evelynn N. Harrington, Tim Philbeck, Stephanie Wilczynski, Fernanda B.M. Priviero, Francis G. Spinale, Robert Clinton Webb, , Fiona Hollis
This study examines sex-specific effects of chronic unpredictable stress on mitochondrial function in the HPA axis of mice, finding reduced mitochondrial respiration in females and increased complex II protein in males.
bioRxiv · Jul 28, 2025 · PreprintNeuroscience