A peripherally restricted cannabinoid 1 receptor agonist provides analgesic benefit from neuropathic pain and a lack of addiction-related behavior
Amie L. Severino, Lindsay M. Lueptow, Emily Ellis, Dania Alkoraishi, Igor Spigelman, Catherine M. Cahill
This study evaluates a peripherally restricted CB1 agonist for neuropathic pain relief and addiction risk, finding it reduces pain without promoting drug-seeking behavior.
bioRxiv · Apr 15, 2026 · PreprintNeuroscience