A mechanistic understanding of the effect of Staphylococcus aureus VraS histidine kinase single point mutation on antibiotic resistance
Liaqat Ali, Salima Karki, Gunavanthi D. Boorgula, Amir Mekakda, Brittnee Cagle-White, Shrijan Bhattarai, Robert Beaudoin, Aryanna Blakeney, Sanjay Kumar Singh, Shashikant Srivastava, May H. Abdel Aziz
This study investigates how a single-point mutation in the VraS histidine kinase of S. aureus affects antibiotic resistance through enzyme kinetics, microbiological, and transcriptomic analyses.
Microbiology Spectrum · Apr 15, 2025Peer-reviewedMicrobiology