Identification of target genes and regulatory networks for bone mineral density GWAS loci through systematic targeting and inhibition
Mohammadjavad Kahlani, Larry D. Mesner, Vedavathi Madhu, Lucia Wagner, Kristyna Kupkova, Hannah J Pitas, Ana C Mello, Samuel Ghatan, Tuuli Lappalainen, Neville E. Sanjana, John A. Morris, Charles R. Farber
The paper identifies target genes and regulatory networks for bone mineral density GWAS loci using STING-seq, linking noncoding variants to gene function in osteoblasts.
bioRxiv · Feb 16, 2026 · PreprintGenomics