Author

Vedavathi Madhu

University of VirginiaORCID 0000-0002-8508-7891Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1

Frequent Co-Authors

Abhijit S. DigheiD· 2 shared Charles R. FarberiD· 2 shared Larry D. Mesner· 2 shared Alexandra MancheliD· 1 shared Ana C Mello· 1 shared Angelo C. LeporeiD· 1 shared Emanuel J. NovaisiD· 1 shared Eric V. BrowniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersSystems Biology

Abhijit S. DigheORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Systems BiologybioRxivPreprintOct 29, 2026

Targeted proteomics informed by long-read RNA-sequencing reveals protein isoform expression associated with bone mineral density

Micah D. Lehe, Vasilii Pavelko, Erin D. Jeffery…·Gloria Sheynkman

This study uses genetics-guided targeted mass spectrometry to detect protein isoforms associated with bone mineral density, confirming their expression in clinical samples.

DOI 10.64898/2026.10.28.759629

humanproteomics

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GenomicsbioRxivPreprintFeb 16, 2026

Identification of target genes and regulatory networks for bone mineral density GWAS loci through systematic targeting and inhibition

Mohammadjavad Kahlani, Larry D. Mesner, Vedavathi Madhu…·Charles R. Farber

The paper identifies target genes and regulatory networks for bone mineral density GWAS loci using STING-seq, linking noncoding variants to gene function in osteoblasts.

1 citation

humanCRISPR screen

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Cell BiologyScience AdvancesPeer-reviewedApr 23, 2025

Neuroimmune changes underscore pain-associated behaviors and disc herniations in SM/J mice

Emanuel J. Novais, Olivia K. Ottone, Eric V. Brown…·Makarand V. Risbud

This study identifies SM/J mice as a model for spontaneous disc herniations and shows neuroimmune changes drive chronic discogenic pain.

9 citationstop 3%

mousescRNA-seq

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