Author

Ana Sastre

Hospital Universitario La Paz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:database / resource· 1 Approach:deep learning· 1

Frequent Co-Authors

Florencia Cidre‐AranaziD· 3 shared Javier AlonsoiD· 3 shared Thomas G. P. GrünewaldiD· 3 shared Anna C. EhlersiD· 2 shared Ashok Kumar JayaveluiD· 2 shared Lianghao MaoiD· 2 shared Tobias FaehlingiD· 2 shared Alina Ritter· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersCancer Biology

Florencia Cidre‐AranazORCID

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3 papers

Recent·Most cited

Functional spatial transcriptomics uncover LMO7 as a fusion-regulated and clinically relevant driver of metastasis in Ewing sarcoma

Veronika Buršić, Heng Luo, Clémence Henon, Lianghao Mao, Anna C. Ehlers, Angelina Yershova, J-Ann M. Lego, Jing Li, Martha J. Carreno Gonzalez, Richard Arndt, Ana Sastre, Javier Alonso, Uta Dirksen, Wolfgang Hartmann, Ashok Kumar Jayavelu, , Florencia Cidre‐Aranaz

The paper identifies LMO7 as a fusion-regulated driver of metastasis in Ewing sarcoma using spatial transcriptomics and integrates clinical data to show its association with poor outcomes.

bioRxiv · Sep 17, 2026 · PreprintCancer Biology

cIAP1 inhibitor of apoptosis is a tumor suppressor in Ewing sarcoma

Florencia Cidre‐Aranaz, Florian H. Geyer, Tilman L. B. Hölting, Kimberley M. Hanssen, Tobias Faehling, Alina Ritter, Malenka Zimmermann, Lianghao Mao, Javier Alonso, Ana Sastre, Ashok Kumar Jayavelu, Maximilian M. L. Knott, Julian Musa, Thomas G. P. Grünewald

This study identifies cIAP1 as a tumor suppressor in Ewing sarcoma, showing that its re-expression inhibits proliferation and tumor growth in vitro and in vivo.

Cancer Letters · Mar 2, 2026Peer-reviewedCancer Biology

Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation

Martin F. Orth, Didier Surdez, Tobias Faehling, Anna C. Ehlers, Aruna Marchetto, Sandrine Grossetête, Richard Volckmann, Danny A. Zwijnenburg, Julia S. Gerke, Sakina Zaïdi, Javier Alonso, Ana Sastre, Sylvain Baulande, Martin Sill, Florencia Cidre‐Aranaz, , Thomas G. P. Grünewald

The paper presents a multi-omics cell line atlas for Ewing sarcoma, identifying new target genes and regulatory mechanisms of EWSR1-ETS fusion oncogenes.

Cell Reports · Dec 1, 2022Peer-reviewedGenomics