Epigenetic Regulation of Chondrogenesis: JMJD3 and UTX as Key Targets for Gene-Modified Mesenchymal Stem Cell Therapy in Cartilage Tissue Engineering
Lyess Allas, Juliette Aury‐Landas, Quitterie Rochoux, Anais Julien, Eva Lhuissier, Marion Lenté, Sybille Brochard, A. Veyssière, Karim Boumédiene, Catherine Baugé
This study investigates the roles of JMJD3 and UTX in chondrogenesis using mesenchymal stem cells and finds JMJD3 is critical for cartilage formation while UTX is dispensable.
Molecular Therapy · Jan 21, 2026Peer-reviewedDevelopmental Biology