Sybille Brochard

This study investigates the roles of JMJD3 and UTX in chondrogenesis using mesenchymal stem cells and finds JMJD3 is critical for cartilage formation while UTX is dispensable.

This study profiles systemic immune changes in a murine OA model, finding reduced MHCII on macrophages and DCs, increased tolerogenic DCs, and shifts in T cell composition.

This study shows EZH2 inhibition reduces cartilage damage, synovial inflammation, and pain in OA by modulating inflammatory, neuroimmune, and osteoimmune pathways.