Author

Anamika Kannan

University of Michigan

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Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Adam S. HelmsiD· 1 shared Alexandre C. PereiraiD· 1 shared Andrea D. ThompsoniD· 1 shared Carolyn Yung HoiD· 1 shared Christopher SemsarianiD· 1 shared Daniel Louis JacobyiD· 1 shared Euan Angus AshleyiD· 1 shared Francesco MazzarottoiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Adam S. HelmsORCID

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1 paper

Recent·Most cited

Computational prediction of protein subdomain stability in MYBPC3 enables clinical risk stratification in hypertrophic cardiomyopathy and enhances variant interpretation.

Andrea D. Thompson, Adam S. Helms, Anamika Kannan, Jaime M. Yob, Neal K. Lakdawala, Samuel G. Wittekind, Alexandre C. Pereira, Daniel Louis Jacoby, Steven D. Colan, Euan Angus Ashley, Sara Saberi, James S. Ware, Jodie Ingles, Christopher Semsarian, Michelle Michels, , SHaRe investigators

The paper uses STRUM to predict subdomain stability in MYBPC3 variants, showing that variants causing misfolding are associated with higher adverse event rates in HCM patients.

Genetics in Medicine · Mar 29, 2021Peer-reviewedGenetics