Author

Anders Karlén

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alberto Inga· 1 shared Andrei L. Okorokov· 1 shared Aparna Vema· 1 shared Clemens Spinnler· 1 shared Eleanor R. Dickinson· 1 shared Elisabeth Hedström· 1 shared Galina Selivanova· 1 shared Joanna Zawacka-PankauiD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alberto Inga

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1 paper

Recent·Most cited

Novel allosteric mechanism of p53 activation by small molecules for targeted anticancer therapy

Joanna Zawacka-Pankau, Vera V. Grinkevich, Mikhail Burmakin, Aparna Vema, Karin Fawkner, Natalia Issaeva, Virginia Andreotti, Eleanor R. Dickinson, Elisabeth Hedström, Clemens Spinnler, Alberto Inga, Lars-Gunnar Larsson, Anders Karlén, Olga Tarasova, Vladimir Poroikov, , Galina Selivanova

This study identifies a novel allosteric mechanism by which small molecules activate p53 by blocking MDM2/MDMX binding, offering a new approach for anticancer therapy.

bioRxiv · Dec 7, 2018 · PreprintCancer Biology