Impact of opioid-based versus opioid-free anaesthesia on postoperative recovery, circulating inflammatory cytokines and brain-derived neurotrophic factor.
Yann Gricourt, Kenneth Lin, Thorsten Althoff, Eileen K. Nguyen, Andrea Mattern, Meenakshi Nair, Tess Leong, Emily Silva, Tristan Grogan, Nicolas Massaly
This study compares opioid-free and opioid-based anaesthesia in mice, finding no significant differences in recovery, inflammation, or BDNF levels.
bioRxiv · Oct 1, 2026 · PreprintAnimal Behavior & Cognition