Eileen K. Nguyen

This study compares opioid-free and opioid-based anaesthesia in mice, finding no significant differences in recovery, inflammation, or BDNF levels.

The paper identifies a GRPR-expressing spinal neuron population that encodes itch and shows that kappa opioid receptor agonists inhibit itch by targeting these neurons.

This study shows that delta-opioid receptor agonists suppress itch while antagonists induce itch, revealing DOR's role in itch modulation in the spinal cord.

The paper investigates the role of mu-opioid receptor-expressing neurons in the periaqueductal gray in modulating pain and itch behaviors through optogenetic and chemogenetic manipulations.

This study investigates the role of Tacr1-expressing ON cells in the RVM in modulating pruriceptive transmission, finding they inhibit itch despite being pronociceptive.

The paper identifies RVM neurons expressing the kappa-opioid receptor that inhibit pain and itch via a descending circuit in mice.

This paper identifies new retinal ganglion cell types and brain nuclei expressing Brn3c using a novel Cre allele, revealing expanded RGC diversity and novel connectivity patterns.

The paper identifies distinct neural pathways from the lateral parabrachial nucleus that mediate different aspects of the pain response, including escape behaviors and aversive memory.