Differential gene regulation in DAPT-treated Hydra reveals molecular pathways dependent on Notch signalling during interstitial cell differentiation and formation of the oral-aboral axis in Hydra.
Jasmin Moneer, Stefan Siebert, Stefan Krebs, Jack F. Cazet, Andrea Prexl, Qin Pan, Celina E. Juliano, Angelika Böttger
This study uses RNAseq to identify genes differentially regulated by Notch signaling inhibition in Hydra, revealing roles in nematocyte development and head organizer formation.
Journal of Cell Science · Jun 14, 2021Peer-reviewedDevelopmental Biology