Workflow and instrumentation for multiscale correlative imaging in voluminous cryogenic specimens
Edoardo D’Imprima, Ievgeniia Zagoriy, Saskia Mimietz-Oekler, Robert Kirmse, Andreas Hallady, Philip Nkemdirim Mbonu, Paolo Ronchi, Martin Jechlinger, Julia Mahamid
This paper introduces a multiscale correlative imaging workflow for cryogenic specimens, enabling fluorescence-guided site preparation and targeted lamellae lift-out for cryo-ET.
bioRxiv · Oct 16, 2026 · PreprintCell Biology