Aging concomitantly reduces skeletal muscle proteome plasticity and hypertrophic responses to resistance training
Dustyn T. Lewis, Max Michel, Mason C. McIntosh, Dakota Tiede, Daniel L. Plotkin, Madison L. Mattingly, Nicholas J. Kontos, George Kontos, breanna Mueller, Bradley A. Ruple, Joshua Godwin, Brad Jon Schoenfeld, Melissa Boersma, Andrew D. Frugé, Christopher Brooks Mobley, , Michael Roberts
This study shows aging reduces proteome plasticity and hypertrophic responses to resistance training in skeletal muscle, but RT partially reverses some aging-related changes.
Medicine & Science in Sports & Exercise · Sep 14, 2026Peer-reviewedPhysiology