Exogenous L6 myotube mitochondrial transplantation attenuates hypertrophy and elicits a unique proteomic signature in phenylephrine-treated H9C2 cardiomyocytes
Nicholas J. Kontos, George J. Kontos, Dustyn T. Lewis, Samuel C. Norton, Bradley A. Ruple, Andreas N. Kavazis, Darren T. Beck, Melissa Boersma, Christopher Brooks Mobley, Danielle J. McCullough, Ahmed Ismaeel, Michael D. Roberts
This study shows that transplanting L6 myotube mitochondria reduces hypertrophy and alters proteomic pathways in phenylephrine-treated H9C2 cardiomyocytes.
bioRxiv · Sep 22, 2026 · PreprintCell Biology