Mason C. McIntosh

Aging concomitantly reduces skeletal muscle proteome plasticity and hypertrophic responses to resistance training

This study shows aging reduces proteome plasticity and hypertrophic responses to resistance training in skeletal muscle, but RT partially reverses some aging-related changes.

Resistance training-induced appendicular lean tissue mass changes are largely unrelated to pre-training bone characteristics in a larger cohort of untrained adults

This study examines if pre-training bone characteristics predict changes in lean tissue mass after resistance training, finding little association.

Skeletal muscle mitochondrial responses to a single bout and six weeks of high load versus high volume resistance training in previously trained men

This study compares mitochondrial mRNA and protein responses to high-load and high-volume resistance training in trained men, finding no differences between the two training paradigms.

Leg immobilization and subsequent recovery resistance training affect skeletal muscle angiogenesis related markers in young healthy adults regardless of prior resistance training experience

This study examines how leg immobilization and recovery resistance training affect skeletal muscle angiogenesis markers in young adults, finding similar molecular responses regardless of prior training experience.

Effects of leg immobilization and recovery resistance training on skeletal muscle-molecular markers in previously resistance trained versus untrained adults

This study examines how resistance training status affects muscle size and molecular markers during leg immobilization and recovery training in young adults.

Skeletal muscle myosin heavy chain protein fragmentation as a potential marker of protein degradation in response to resistance training and disuse atrophy

This study examines how resistance exercise and disuse atrophy affect myosin heavy chain (MyHC) protein fragmentation in humans, finding increased fragmentation post-exercise and during atrophy, with adaptive responses after training.

Resistance Training Diminishes Mitochondrial Adaptations to Subsequent Endurance Training

This study examines how resistance training before endurance training affects mitochondrial adaptations, finding that prior resistance training impairs mitochondrial responses to subsequent endurance training.

Skeletal muscle DNA methylation and mRNA responses to a bout of higher versus lower load resistance exercise in previously trained men

This study compares DNA methylation and mRNA responses to lower- versus higher-load resistance exercise in trained men, finding similar gene expression and methylation patterns despite differences in exercise intensity.