Author

Andrew Allen

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Arturo AndradeiD· 1 shared Fan GaoiD· 1 shared Glen Satten· 1 shared Henny Haensgen· 1 shared Henry Richard Johnston· 1 shared Hongik HwangiD· 1 shared Jennifer Qian Pan· 1 shared Lei J. Ding· 1 shared

Activity by Year

2016-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Arturo AndradeORCID

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2 papers

Recent·Most cited

A schizophrenia risk gene, NRGN, bidirectionally modulates synaptic plasticity via regulating the neuronal phosphoproteome

Hongik Hwang, Matthew J. Szucs, Lei J. Ding, Andrew Allen, Henny Haensgen, Fan Gao, Arturo Andrade, Jennifer Qian Pan, Steven A. Carr, Rushdy Ahmad, Weifeng Xu

This study shows that NRGN modulates synaptic plasticity by regulating the phosphoproteome, linking it to schizophrenia and autism-related pathways.

bioRxiv · Nov 29, 2018 · PreprintNeuroscience

Testing Rare-Variant Association without Calling Genotypes Allows for Systematic Differences in Sequencing between Cases and Controls

Yi-Juan Hu, Peizhou Liao, Henry Richard Johnston, Andrew Allen, Glen Satten

The paper introduces a likelihood-based method to test rare variant associations without genotype calling, showing robustness to sequencing differences and identifying novel variants in childhood obesity.

PLOS Genetics · May 6, 2016Peer-reviewedBioinformatics