Motor protein disruption critically alters organelle trafficking, NMJ formation, and excitation contraction coupling.
Himanshu Bansal, Tadros A. Hana, Andrew H. Michael, Sevinch U. Kamaridinova, J. Bransford, Kiel G. Ormerod
This study identifies kinesin 1 and 3 as critical regulators of organelle trafficking in motor neurons, leading to morphological and functional disruptions in neuromuscular junctions and behavior.
bioRxiv · Jun 10, 2025 · PreprintNeuroscience