BiochemistryProceedings of the National Academy of SciencesPeer-reviewed
Structure and dynamics of a pentameric KCTD5/Cullin3/Gβγ E3 ubiquitin ligase complex
Duc Minh Nguyen, Deanna H. Rath, Dominic Devost…·Gilbert G. Privé
The paper presents the cryo-EM structure of a pentameric KCTD5/CUL3/Gβγ E3 ubiquitin ligase complex, revealing its dynamic architecture and mechanism for ubiquitylating Gβγ.