Impaired Hippocampal-cortical interactions during sleep and memory reactivation without consolidation in a mouse model of Alzheimer’s disease
Sarah Danielle Cushing, Ivan Skelin, Shawn C. Moseley, Alina C. Stimmell, Jessica R. Dixon, Andreza S. Melilli, Leonardo A. Molina, Bruce L. McNaughton, Aaron A. Wilber
The paper investigates hippocampal-cortical interactions during sleep in a mouse model of Alzheimer’s disease and finds reduced SWR-DW coupling correlates with impaired spatial memory.
Current Biology · May 28, 2020Peer-reviewedNeuroscience